Searchable abstracts of presentations at key conferences in endocrinology

ea0038p224 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2015

The hypoglycaemic and antioxidant properties of oleanolic acid ameliorate blood pressure and kidney function of experimental animals

Khathi Andile , Mbatha Bonisiwe , Musabayane Cephas T

The wide range of phytochemicals in medicinal plants serves as sources of bioactive compounds for treatment diabetic complications. We investigated whether Syzygium aromaticum-isolated oleanolic acid (OA) has beneficial effects on some diabetic complications in STZ-induced diabetic rats. We used experimental models of hypertension [spontaneously hypertensive (SHR) and Dahl salt-sensitive (DSS)] rats to explore the effects of OA on mean arterial blood pressure (MAP) and renal f...